Karyopharm Therapeutics Inc risk profile
38 Normal where most of the sector sits
Measured 1 September 2026 from KPTI's filed statements. Recomputed nightly.
38 (Normal), driven by Leverage and coverage at 94, over 5 weighted categories on the MANUFACTURER profile.
What is measured
| Mechanism | Reading | Band | Direction | Driver |
|---|---|---|---|---|
| Market expectation | 80 | Acute | Volatile | One-year price volatility — 115.6% |
| Operating pressure | 1 | Contained | Easing | Costs outgrowing revenue — -11.1 percentage points |
| Cash conversion | 57 | Elevated | Easing | Free-cash-flow margin — -51.6% |
| Leverage and coverage | 94 | Acute | Worsening | Net debt to EBITDA |
| Competitive position | 26 | Normal | Stable | Revenue-growth gap against peers — -22.2 percentage points |
| Concentration | Reads identified supplier spend, customers above the 10% disclosure threshold and revenue by region. No reading is stored for this company. | |||
These are descriptive readings of disclosed mechanisms, not investment advice, and not a prediction. A band says where a measured input sits, never what to do about it or what happens next.
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Financials, valuation and price history for Karyopharm Therapeutics Inc